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These results indicate that statins regulate the GLUT4 expression via influencing mevalonate pathway and some intermediate metabolites in mevalonate pathway play an important role in regulating transcription levels of GLUT4

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[1] In the Phase 2 trial published in the New England Journal of Medicine in 2023, participants receiving the highest dose (12 mg weekly by subcutaneous injection) achieved a mean 24.2% body-weight reduction at 48 weeks