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This is in agreement with previous studies showing that LAB isolated from dairy products, pickles, chickens, and meats can tolerate high NaCl concentrations 65,66,67

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[Note: This reaction is analogous to the formation of cyclic AMP by adenylate cyclase, except that this guanylate cyclase is not membrane associated.] The resultant rise in cGMP causes activation of protein kinase G, which phosphorylates Ca 2+ channels, causing decreased entry of Ca 2+ into smooth muscle cells