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10.1016/j.ejmcr.2024.100240 54 CiprianoA.VivianoM.FeoliA.MiliteC.SarnoG.CastellanoS.et al (2023)

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Endoplasmic reticulum stress If not quickly rectified, any of the above stresses activates the ER stress- unfolded protein response (UPR) which, in turn, exacerbates oxidative stress and elicits inflammation by activating stress response genes such as NF-kB (9, 122)