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The whole purpose of enriching for PRP is to reverse the RBC-to-platelet ratio to achieve 95% platelets and 5% of RBCs.[11] Enriched fraction of PRP is known to contain high level of growth factors and cytokines that promote tissue regeneration and healing and also reported to be effective in tissue reparative efficacy.[12] The primary roles of platelets are to form aggregated and also contribute to homeostasis through adhesion, activation and aggregation