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Notably, genera such as Neisseria , Lautropia , and Agrobacterium were elevated, along with associated toxic serum metabolites, including 4-chlorophenylacetic acid, 5-sulfoxymethylfurfural, and estradiol valerate, which may contribute to gastrointestinal disturbances

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Of relevance, the chemokine ligand CXCL4/PF4 inhibits CD163 in macrophages, compromising their phagocytic function and exacerbating the progression of atherosclerosis (154)