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Unlike men who may see testosterone suppression, women often experience disrupted menstrual cycles due to the caloric deficit and rapid body composition changes

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Severe life-threatening disease involves anemia, massive heart and lung involvement, significant kidney damage, acute inflammation of the vascular system in the extremeties or gastrointestinal tract, Central Nervous System disorders and formation of purple patches on the skin and mucous membranes (thrombocytopenic purpura)