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Nonetheless, they are understood to be related to structural changes in the patient’s joint environment, continued disease progression, ectopic secretions, and peripheral nerve damage and dysfunction due to increased excitability of damaged afferent injury receptors, which manifest as neuropathic pain (71, 72)

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Synthesis and characterization of polyethyleneimine-coated MXene quantum dots Polyethyleneimine-coated MXene quantum dots (PEI-MQDs) were synthesized from Ti 3 C 2 MXene powder (Jilin Science and Technology) and 25 mg of polyethyleneimine (PEI) (Sigma, MV 1800)