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During phase I, the subjects begin forcefully exhalating against a closed airway, the intrathoracic pressure suddenly increases which leads to the brief increase in the systemic arterial blood pressure (ABP) and cerebral bloof flow

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For the literature search, we used the terms “dietary herbal products AND anti-inflammatory,” dietary herbal products AND neuroprotection,” “dietary herbal products AND brain,” “dietary herbs and AND brain,” “dietary herbs AND anti-inflammatory,” dietary herbal extracts AND anti-inflammatory “and several other matching terms