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Another report confirmed that folate deprivation significantly inhibits cell proliferation in the hippocampus, migration, survival, differentiation, transport of vesicles and plasticity of synapses [48]

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As early as 1990, Bowers and colleagues showed that the joint administration of a GH-releasing peptide and GHRH produces a GH peak far above either substance alone, and that this occurs via separate mechanisms (Bowers et al., 1990)