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eNOS deletion impairs mitochondrial quality control and exacerbates Western diet-induced NASH

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Importantly, endothelial dysfunction has been shown to be of prognostic significance in predicting vascular events [11, 12], so endothelial function testing may potentiate the detection of cardiovascular diseases such as myocardial infarction, peripheral vascular disease, ischemic stroke, and others [13, 14]