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The clinical definition of hypogonadism requires both laboratory evidence (typically total testosterone below 300 ng/dL on two separate morning fasting draws) and clinical symptoms (fatigue, low libido, erectile dysfunction, loss of muscle mass, depression, cognitive fog)
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In short, lack of water on a daily basis can cause tiredness, energy level to be low, headaches, constipation, dry skin, chapped lips as well as other issues