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Together with its oxidized partner (GSSG), GSH maintains cellular redox homeostasis 1 , regulates protein functions through S -glutathionylation 2 , contributes to iron-sulfur cluster maturation 3 , and acts as a signalling molecule to directly activate gene expression 4,5

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Annu Rev Neurosci 34:185–204 [DOI] [PMC free article] [PubMed] [Google Scholar] O’Brien RJ, Wong PC (2011b) Amyloid precursor protein processing and alzheimer’s disease