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Then, in a series of steps, two 1C units and one glycine unit are added to form inosine monophosphate (IMP), which is then further converted to different purine nucleotides (adenosine and guanosine monophosphate) [52]

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Extended half-life and prolonged receptor engagement: One of the defining features of IGF-1 LR3 is its structural modification that reduces binding to IGF-binding proteins