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The modified t- statistic is t = (mean group 1—mean group 2)/[s x (1/n 1 + 1/n 2 ) 1/2 ] where s 2 = the mean square within groups term from the ANOVA (the square root of this value is taken for the modified t-statistic formula) and n 1 and n 2 are the number of rats in each group