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Amplification of the CDK5 (cell cycle protein 5) gene or its major activators, p35 and p39 , was observed in 67% of PDAC cases
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The observed lesions such as rapture, sloughing off of meninges, and hemorrhage was indicative of primary injury while the inflammatory responses that may cause neuronal loss, axonal injury, and impairment of synaptic plasticity indicate the secondary injury process ( The hippocampus is an essential brain region concerned with several vital functions, such as cognition, learning, and memory