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Metformin plus L-carnitine enhances brown/beige adipose tissue activity via Nrf2/HO-1 signaling to reduce lipid accumulation and inflammation in murine obesity - PMC

10.1016/S0149-7634(03)00033-2 Neurosci

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A study indicates that 6% to 15% of opioid-naïve post-op patients became chronic opioid users after major or minor surgery, including 4% of those who underwent total hip arthroplasty and 8% of total knee arthroplasty