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Cross-referencing this list with the Orange Book patent listings reveals not just which patents are being challenged but which claims within those patents the generic filer believes are invalid or not infringed

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One such condition, Amyotrophic lateral sclerosis (ALS) is a chronic degenerative disease of motor neurons, and its pathogenesis has been linked to an accumulation of intracellular protein, lipid and DNA damage due to impaired resilience to oxidative stress 86