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Since FRα is responsible for over 60% of folate transport in trophoblast cells, and plays a crucial role in determining intracellular folate status [28,105], it is rational to speculate that FRAbs may interfere with the bio-behaviors of trophoblast cells mediated by FRα

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Mechanistic endpoints were recorded when available, including markers of inflammation, angiogenic activity, collagen organization, and bone remodeling