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Both routes can effectively raise serum B12 levels in many individuals, as high-dose oral B12 (1000-2000 micrograms) can be absorbed by passive diffusion even without intrinsic factor

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[DOI] [PMC free article] [PubMed] [Google Scholar] 17.Petruzzelli M.G., Marzulli L., Margari F., De Giacomo A., Gabellone A., Giannico O.V., Margari L