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Ferroptosis has been associated with pathological cell death in various degenerative diseases, such as Alzheimer's disease (AD), Huntington's disease (HD) and Parkinson's disease (PD), as well as cancer, stroke, cerebral hemorrhage, renal degeneration, spinal cord injury (SCI) and TBI [11–13]

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The pharmacokinetics of bupropion, which is extensively metabolized by the CYP450 (CYP2B6), was not affected by moderate (~ 0.3–0.4 g/L) nor by high (~0.8 g/L) BACs (276)