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In the classical nuclear import pathway, cytoplasmic cargos containing a nuclear localization signal (NLS) assemble into a trimeric importin β:α1:NLS-cargo complex, which docks to the nuclear pore complex (NPC) and moves through the NPC channel due to importin β avidity for phenylalanine-glycine-rich nucleoporins (FG-nups) 7,8

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COUNT:30 Capsules

Furthermore, elevated concentrations of MMPs, enzymes known to degrade glycocalyx components, were detected in both cerebrospinal fluid (CSF) and circulating blood