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10.1136/gutjnl-2016-312574 Summary Keywords proton pump inhibitors, digestive diseases, microbiota, intestinal flora, Clostridium difficile , inflammatory bowel disease, short-chain fatty acids Citation Tian L, Huang C, Fu W, Gao L, Mi N, Bai M, Ma H, Zhang C, Lu Y, Zhao J, Zhang X, Jiang N, Lin Y, Yue P, Yuan J and Meng W (2023) Proton pump inhibitors may enhance the risk of digestive diseases by regulating intestinal microbiota