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Expanding the Clinical and Mutational Spectrum of Recessive AEBP1-Related Classical-Like Ehlers-Danlos Syndrome
SS-31 may also inhibit the opening of a channel in the inner membrane called the mitochondrial permeability transition pore (mPTP), at least in rodents.5 Because mPTP opening has been implicated in neuronal death, SS-31’s inhibitory action is a potential mechanism of action for the peptide’s cognitive health benefits.6 Furthermore, several studies have concluded that SS-31 is capable of scavenging mitochondrial reactive oxygen species, making it a potent antioxidant.19 Its antioxidant mechanism of action isn’t yet fully understood, but one group of researchers has theorized that it has to do with an ability to activate autophagy20 — a cellular recycling process that promotes efficient function and which is critical for mitigating oxidative stress.21 Current therapeutic uses of SS-31 Clinical studies on SS-31 support its use as a treatment for multiple aging-related changes, including those related to cognition, physiology, and vision
Workarea: sheep-vitamins-supplements
Capsule Count:180
For orthotopic liver tumor models, the Hepa1–6 cells (5 × 10 6 ) were suspended in 25 μL of Matrigel (Sigma-Aldrich) and inoculated into the liver parenchyma of the left lobe for in situ liver tumor model ( n = 6)
