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What to do about B12 deficiency if injections don't help?

Patients who have early Leber's disease (hereditary optic nerve atrophy) have been found to suffer severe and swift optic atrophy when treated with vitamin B12

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“They get early menopause from chemotherapy or they get aromatase inhibitor-associated musculoskeletal syndrome, and then they can't use this medication.” What to do (and not do) Physical therapy for frozen shoulder focuses mainly on stretching and manual therapy, which may differ depending on what stage you’re in, and can often cause discomfort