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Loss of NAD + levels results in impairment of mitochondria function, which leads to failure of essential metabolic processes ( + pools can offer significant improvements of pathologic states ( + levels directly affects the metabolism of the body’s three major energy substances: sugar, fat, and protein, inducing MetS ( + levels across various mouse tissues, including adipose (Yoshino et al., 2011), skeletal muscle ( et al

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Renal IRI or sham surgery was performed prior to the glucose tracing experiment