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Magnesium: 400-600mg daily (as glycinate or threonate) stabilizes mast cells Zinc: 30-50mg daily (with 2-3mg copper) modulates immune function B-complex: Especially Vitamins B6 (as P5P) and B12 (as methylcobalamin), which support histamine breakdown Most people notice reduced peptide reactivity within 4-8 weeks of systematically addressing these root causes

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doi: 10.1177/0091270004271253