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Other Antioxidants Compounds Honokiol, a lignan identified in Magnolia officinalis, restored the hepatic GSH content and SOD activity and reduced inflammatory cytokine levels in an hepatic injury animal model, whereas berberine, a benzyl isoquinoline alkaloid in the Coptis genus, raises the levels of GSH and PGC1a and normalized CYP2E1 expression in an animal model of alcohol administration [102]