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Vitamin B12 Deficiency: A Fact Sheet on Signs, Treatment and Benefits

In methyl vitamin B12 deficiency, there is reduced production of S-Adenosylmethionine (SAM), and the activity fo the enzyme cystathionine beta synthase is reduced, thus leading to reduced transfer of the sulphur from methionine into the sulphation cycle, with a resultant lack of production of Glutathione

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Despite the popularity of these interventions, it is important to note that scientific evidence varies