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Vitamin B-12 is an essential water-soluble nutrient that is crucial for many bodily functions. Key Benefits of Vitamin B-12: • Red Blood Cell Formation & Anemia Prevention: essential for producing healthy, properly

124 The British Society of Haematology published its guidelines on vitamin B12 and folate screening in 2014, at which time they stated that “no definitive advice can be given on the desirable frequency of monitoring” of vitamin B12 in those with T2DM having metformin therapy but recommended that serum B12 be measured “in the presence of strong clinical suspicion of deficiency”, 149 which we would opine may be difficult since deficiency is often asymptomatic

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Advanced age is often associated with reduced muscle mass and regenerative capacity, perhaps due in part to less effective muscle stem cells