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10.1016/j.redox.2018.02.025 Summary Keywords epigenetic modification, DNA methylation, histone modification, non-coding RNAs, melatonin Citation Monayo SM and Liu X (2022) The Prospective Application of Melatonin in Treating Epigenetic Dysfunctional Diseases

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UPS exerts a role in protein degradation, which in turn regulates the synaptic plasticity in neurons and maintains neuronal activity, and signaling between neurons is dependent on the regulation of UPS (Kumari et al., 2017) (Figure 5)