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In other cases, depending on temperature and vacuum pressure, the peptide may appear as crystals, small clumps, or thin films — however, the actual peptide amount is always identical

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Besides, mass analyzers, such as TOF (Time-of-Flight), Q-TOF (Quadrupole-Time-of-Flight), and LTQ (Linear Trap Quadrupole)-Orbitrap, are also often incorporated in many different hybrid detection systems, especially in HR-MS/MS due to their ability to remarkably increase the informative power of the MS detectors (Gaudêncio et al