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Solubilidad: Completamente soluble en agua
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1 Introduction 1.1 Breast cancer: genetic factors and therapeutic advancements Breast cancer (BC) is the most commonly diagnosed malignancy in 30% of women each year and the risk to develop BC is known to have a hereditary component with a mean diagnostic age of 62 years with a higher risk among black women ( BRCA1 , BRCA2 , p53 , PTEN , ATM , NBS1 , and LKB1 ) ( CYP1A1 , CYP2D6 , and CYP19 ) ( GSTM1 and GSTP1 ) ( ADH1C and MTHFR ) ( XRCC1 , XRCC3 , and ERCC4/XPF ) ( PR , ER , TNF-α , or heat shock protein 70 ( HSP70 )] ( BRCA1 and BRCA2 (Breast Cancer 1 and 2) genes are present in approximately 80-90% of all hereditary BCs ( HER2 (human epidermal growth factor receptor 2)/neu gene, one of four members of the epidermal growth factor receptor (EGFR) family, was identified as a contributor to the development of breast cancer in patients through the ground-breaking work of William Muller et al
