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Therefore, we speculated that CBS is nonfunctional under supraphysiological cystine concentrations and investigated its function in a customized culture media containing cystine at a physiological concentration of 50 μM or less

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Scavenging mechanisms for ROS involve these enzymes: SOD, CAT, APX, MDHAR, DHAR, glutathione peroxidase (GPX), and GR (Payton et al., 2001)