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Benefits Improved tissue perfusion and healing Growth factor up-regulation Promotes tendon and collagen synthesis Accelerates muscle and bone healing Reduces inflammation Heals stomach and intestine ulcers, leaky gut, IBS, gut dysmotility Dosing Subcutaneous or Near Site of Injury 200 mcg – 600 mcg Once a day Evening preferred 8 weeks ON

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An in-depth mechanistic study has shown that activation of the BDNF signaling pathway significantly increases protein levels of neurexin-β and neuroligin 1 and synaptic plasticity in the hippocampus, possibly involving TrkB/PI3k/AKT/mTOR in this process [54]