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In published preclinical and clinical research on CJC-1295 (DAC variant), doses ranging from 30 to 250 micrograms per kilogram have been characterised across single-dose and multi-dose administration regimens, with subcutaneous and intravenous routes most common (PMID 16352683, PMID 16822960)

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however, more recently, the PREDIMED study did not find any significant association [58]