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Greater than 99.9% of the BSA mass in the CB flowed through during loading, but at higher pH, increasing BSA was detected in the GSH wash and elution fractions (Figure 4B)

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It should be noted that other reasons for choosing HBsAg loss as the anchor for functional HBV cure include the low risk of virologic relapse when treatment is stopped, given the desire for finite therapy, the potential for incremental clinical benefit compared with HBV DNA suppression without HBsAg loss,24 and removal of the stigma of HBV infection