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It has been shown that GSTT1 expression is significantly upregulated in chemotherapy-resistant serous ovarian cancer (SOC) cells and that inhibition of GSTT1 expression negatively influenced the proliferation of SOC cells, thereby enhancing their sensitivity to paclitaxel/carboplatin [116]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 310.Van Goethem, G., Dermaut, B., Löfgren, A., Martin, J