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6 Importantly, patients categorized as high complexity were undertreated, which strongly suggests that practice is not aligned with current COPD guidelines

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3.1.2 Indirect effects Indirect probiotic interaction with epithelial cells involves a variety of metabolites such as exopolysaccharides, bile acid derivatives, and SCFAs, which play significant roles in the preservation of intestinal homeostasis, immune system regulation, and strengthening of the epithelial barrier