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While there is not a lot of research comparing the two side by side, some In a 2021 study, the researchers noted that those who injected semaglutide showed more of a reduction in body weight compared to other people who took other approved weight loss medications, such as phentermine

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In the liver, a major organ in the metabolism of various compounds, xenobiotics are generally converted to the hydrophilic form by Phase I (oxidation) and Phase II (conjugation) reactions, and are subsequently excreted into the extracellular space by the Phase III (elimination) system 9 such as ATP-binding cassette sub-family C member 2 (ABCC2) and ABCG2