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Similar increase in prefrontal glutamate has been documented with acute systemic ketamine in healthy volunteers with 1 H-MRS
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doi: 10.3389/fphar.2025.1651219 Received 21 June 2025 Revised 09 October 2025 Accepted 10 October 2025 Published 17 November 2025 Volume 16 - 2025 Edited by Mariangela Marrelli, University of Calabria, Italy Reviewed by Francisco Cruz-Sosa, Universidad Autónoma Metropolitana, Mexico Maria Rosaria Perri, National Research Council of Italy, Italy Updates Copyright © 2025 Liu, Yu, Dou, Shen, Li, Liu, Xie, Zeng, Feng, Huang and Zhu