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Additionally, lipoic acid increased mitochondrial biogenesis through triggering AMP-activated protein kinase (AMPK)-induced transcription factor PGC-1α activation in skeletal muscle of aged mice (48)

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In one study, conducted with rats, glutathione was found to reduce the toxic effects of lead and cadmium.⁶ It can also bind with mercury, which causes various problems when accumulated in the body.⁷ Other studies suggest glutathione can help the body detoxify from persistent organic pollutants, which can build up in the body and cause damage.⁸ 3

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