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Excess glucose enhances activation of the hexosamine pathway, a subset of the glycolytic pathway, and the polyol pathway, a commonly upregulated pathway in DM that converts glucose to sorbitol (Bhatti et al., 2022

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After three days' exposure of snails (Physa sp.) to the same concentration of benzo [a] pyrene with or without piperonyl butoxide at 0.0025 mg/litre, parent benzo [a] pyrene represented 88% in the absence of the inhibitor and 85% in its presence