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For the researcher who has been quantifying cysteine by HPLC with dual electrochemical detection—a method that delivers precision but requires a dedicated chromatography system, per-sample run times exceeding 20 minutes, and operator training that most metabolism laboratories do not possess—the shift from HPLC to microplate-based colorimetric detection is not a compromise

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Onopiuk A, Tokarzewicz A, Gorodkiewicz E