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This includes avoiding substances that are known to cause a strong inflammatory reaction whenever possible

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(2009) hypothesized that pindolol (20 mg p.o.), a mixed β-adrenergic and 5HT 1A receptor antagonist, administered one hour prior to MDMA (1.6 mg/kg p.o.) would affect MDMA-induced affective, cognitive, and cardiovascular responses (Hasler et al